Gut Microbial Markers

Providing a snapshot of the waste products of yeast, fungus, bacteria and other metabolic pathways present in your urine. T

The health of the microbiome impacts digestion, absorption of nutrients, immune system, detoxification and brain function.

• Yeast & Fungal Markers: Evaluates for overgrowth of candida and mold. Elevations of one or more metabolites indicate a yeast/fungal overgrowth.

• Bacterial balance: Evaluate the levels of expected or opportunistic bacteria in the gut to assess dysbiosis

• Clostridia Bacteria: Identify stubborn pathogenic bacteria present

• Oxalate Metabolites: Oxalic acid and endogenous oxalate (usually yeast, mold or diet related)

• Glycolytic Cycle Metabolites: Identify mitochondrial dysfunction affecting energy production

Mitochondrial Markers:Amino Acid & Krebs Cycle Metabolites

The power house of each cell in the body that help to generate energy (ATP), stress to this cycle from the toxins from candida, bacteria, oxalate, heavy metals and environmental chemicals can lead to low energy, poor exercise recovery and increased oxidative stress.

Neurotransmitter Metabolites:Phenylalanine, Tyrosine & Tryptophan

Chemical messengers in the brain that impact mood and sleep. Identify issues in tryptophan metabolism which can contribute to serotonin imbalance and excess quinolinic acid production. The relationship between two important brain chemicals dopamine and norepinephrine is critical for attention, focusing, mood, calmness, and other nervous system functions. Deficiency or excess of serotonin can impact mood, fine and gross motor skills, calmness, and sleep.

Pyrimidine Metabolites (Folate Metabolism)

Markers uracil and thymine help indicate of folate imbalance. Folate is linked to the methylation cycle that supports the inner workings of cells related to DNA function and metabolism. Poor folate metabolism can lead to cognitive problems.

Ketone and Fatty Acid Oxidation

Ketones are breakdown products of fatty acid metabolism. When fat is used as an energy source it is converted into ketones in the liver by a process called ketogenesis. Elevations in ketones can lead to GI upset like vomiting and diarrhea.

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Nutritional Markers

Identify nutrient imbalances

In order for the body to run effectively, it needs the right level of vitamins and minerals to act as cofactors for enzymatic reactions. Without enough of these nutritional cofactors (or if someone has genetic mutations that affect how well their enzymes work), these chemical pathways are unable to function optimally.

• Vitamin B12

• Vitamin B6

• Vitamin B5

• Vitamin B2 (Riboflavin)

• Vitamin C

• Vitamin Q10 (CoQ10)

• N-Acetylcysteine (NAC) - key antioxidant precursor for glutathione

• Biotin (vitamin H)

Other Markers

This is a large test, including 79 markers. Further markers include Detoxification Capability, Amino Acid Metabolites, and Mineral Metabolism.